Visit our Scientific Research Area: a section dedicated to professionals in the field, where you can find official resources—official documents, publications, and advanced research—on the scientific research topics of the synbrAIn team.

Machine learning- and statistical-based voice analysis of Parkinson’s disease patients: A survey

The preliminary diagnosis and evaluation of the presence and/or severity of Parkinson’s disease is crucial in controlling the progress of the disease.

Continue ReadingMachine learning- and statistical-based voice analysis of Parkinson’s disease patients: A survey

SLEEP-SEE-THROUGH: Explainable Deep Learning for Sleep Event Detection and Quantification From Wearable Somnography

Evidence is rapidly accumulating that multifactorial nocturnal monitoring, through the coupling of wearable devices and deep learning, may be disruptive for early diagnosis and assessment of sleep disorders.

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Designing Logic Tensor Networks for Visual Sudoku puzzle classification

We analyze the application of logical tensor networks to the task of visual Sudoku classification and discuss various alternatives.

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Artificial Intelligence-Based Voice Assessment of Patients with Parkinson’s Disease Off and On Treatment: Machine vs. Deep-Learning Comparison

Parkinson’s Disease (PD) is one of the most common non-curable neurodegenerative diseases. Diagnosis is achieved clinically on the basis of different symptoms with considerable delays from the onset of neurodegenerative processes in the central nervous system.

Continue ReadingArtificial Intelligence-Based Voice Assessment of Patients with Parkinson’s Disease Off and On Treatment: Machine vs. Deep-Learning Comparison

The DarT/DarG Toxin-Antitoxin ADP-Ribosylation System as a Novel Target for a Rational Design of Innovative Antimicrobial Strategies

In this perspective, we discuss the structural and mechanistic aspects of DarT/DarG toxin–antitoxin-mediated control of DNA ADP-ribosylation. In addition, we then address the pathogenic role of the DarT/DarG TA pair as well as the therapeutic perspectives that the modulation of this specific ADP-ribosylation signalling may have.

Continue ReadingThe DarT/DarG Toxin-Antitoxin ADP-Ribosylation System as a Novel Target for a Rational Design of Innovative Antimicrobial Strategies

A Fuzzy-Based Clinical Decision Support System for Coeliac Disease

Coeliac disease (CD) is a permanent inflammatory disease of the small intestine characterized by the destruction of the mucous membrane of this intestinal tract. Coeliac disease represents the most frequent food intolerance and affects about 1% of the population, but it is severely underdiagnosed.

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How resistant are levodopa-resistant axial symptoms? Response of freezing, posture, and voice to increasing levodopa intestinal infusion rates in Parkinson disease

Treatment of freezing of gait (FoG) and other Parkinson disease (PD) axial symptoms is challenging. Systematic assessments of axial symptoms at progressively increasing levodopa doses are lacking. We sought to analyze the resistance to high levodopa doses of FoG, posture, speech, and altered gait features presenting in daily-ON therapeutic condition.

Continue ReadingHow resistant are levodopa-resistant axial symptoms? Response of freezing, posture, and voice to increasing levodopa intestinal infusion rates in Parkinson disease

Detecting Emotions from Illustrator Gestures —The Italian Case

The evolution of computers in recent years has given a strong boost to research techniques aimed at improving human–machine interaction. These techniques tend to simulate the dynamics of the human–human interaction process, which is based on our innate ability to understand the emotions of other humans. In this work, we present the design of a classifier to recognize the emotions expressed by human beings, and we discuss the results of its testing in a culture-specific case study. The classifier relies exclusively on the gestures people perform, without the need to access additional information, such as facial expressions, the tone of a voice, or the words spoken. The specific purpose is to test whether a computer can correctly recognize emotions starting only from gestures. More generally, it is intended to allow interactive systems to be able to automatically change their behaviour based on the recognized mood, such as adapting the information contents proposed or the flow of interaction, in analogy to what normally happens in the interaction between humans. The document first introduces the operating context, giving an overview of the recognition of emotions and the approach used. Subsequently, the relevant bibliography is described and analysed, highlighting the strengths of the proposed solution. The document continues with a description of the design and implementation of the classifier and of the study we carried out to validate it. The paper ends with a discussion of the results and a short overview of possible implications.

Continue ReadingDetecting Emotions from Illustrator Gestures —The Italian Case

Obesity and Gastro-Esophageal Reflux voice disorders: a Machine Learning approach

Automatic assessment of speech disorders is a cutting-edge topic in vocal analysis. Recent studies indicated possible connections between eating disorders and voice alterations.

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