Suppression of ADP-ribosylation reversal triggers cell vulnerability to alkylating agents
This study investigates how the suppression of ADP-ribosyl inversion enhances the vulnerability of cancer cells.... Read more.
Exploitation of DarT/DarG biology for a rational design of antimicrobial agents
Let's discuss the structure and mechanistic aspects of toxin- and antitoxin-mediated control, as well as therapeutic prospects.... Read more.
The DarT/DarG Toxin-Antitoxin ADP-Ribosylation System as a Novel Target for a Rational Design of Innovative Antimicrobial Strategies
In this perspective, we discuss the structural and mechanistic aspects of DarT/DarG toxin–antitoxin-mediated control of DNA ADP-ribosylation. In addition, we then... Read more.
