Oxidative stress

Y0-4-Molecular mechanisms of H0-1 up-regulation in neuroblastoma cell responde to oxidative stress

In this study, we evaluated the involvement of the molecular mechanisms of HO-1 induction in NB cell response to OS, analyzing its main activator Nrf2 and its main repressor Bach1.

Continue ReadingY0-4-Molecular mechanisms of H0-1 up-regulation in neuroblastoma cell responde to oxidative stress
Neuroblastoma

P-182-miRNA494 downregulation increases neuroblastoma sensivity to oxidative stress

Neuroblastoma cells (NB) are able to counteract oxidative stress (OS) through the activation of antioxidant defense mechanisms among which Nrf2/HO-1 system plays a crucial role.

Continue ReadingP-182-miRNA494 downregulation increases neuroblastoma sensivity to oxidative stress

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